Mana drain not allowed to be played
Wasn't given option to counter with mana drain, had two open blue, it was my turn. Both times I had a deathrite shaman out that it was giving me the option to use but when I tried multiple times to forcibly drag mana drain from my hand to enter the stack nothing would happen. Nothing was uncounterable. There was no cancer of souls or anything that would have pre ented my interaction.

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Rezzahan#77802 commented
Teferi, Time Reveler: "Each opponent can cast spells only any time they could cast a sorcery."
This means, that you cannot respond to something on the stack, since sorcery timing requires the stack to be empty. Making all counterspells useless.