Opponent's Creature didn't die when It was given -X/-X
Was in a win or go home game of a draft and Exhausted Winter, Cursed Rider's Ability after chump blocking a Sunmare to make it a 7/4 after combat damage (was originally a 7/8. X =4 to give all non artifact Creatures -X/-X. Opponent had previously given it indestructible but was under the impression the rule was that -X/-Xing a creature Below its toughness got around Indestructibility and Sent it to the graveyard. Opponent was then able to use this bug to win the game since I had to waste a Stun counter spell on the Sunmare instead of stunning their artifact Creature to prevent crewing, we both flooded for 4 turns after that so I should have been able to Punch through for lethal if they didn't have the ability to Crew their vehicle and this cost me my draft. I am very upset about it.

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Rezzahan#77802 commented
Damage to a creature does not reduce toughness. Arena just displays it that way, because damage can accumulate on a creature over the course of a turn, so the number is what is still needed in DAMAGE to kill the creature. But the creature still has its full toughness. Toughness redcution lowers the number to which the marked damage is compared. When indestructible comes into play, though, toughness reduction to 0 or less can kill it, but it has to be a FULL redcution of toughness. Damage is irrelevant, since lethal damage marked on a creature with toughness greater than 0 will cause destruction, which indestructible makes impossible, so such a creature stays alive.